Catalytic enantioselective Conia-ene reaction.
نویسندگان
چکیده
An enantioselective intramolecular Conia-ene reaction of beta-dicarbonyl compounds and alkynes to afford methylene cyclopentanes is described. The reaction employs a DTBMSegphos-Pd(II)/Yb(III) dual catalyst system that allows for the asymmetric synthesis of all-carbon quaternary centers and generates a product containing an alkene that can be further manipulated.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 127 49 شماره
صفحات -
تاریخ انتشار 2005